Phase separation of cellulose derivatives during extrusion – one way to enable the next generation drugs
Treesearch research themes:
4-material concepts
Project partners:
AstrZeneca, Chalmers
Funding:
VR
Status:
Ongoing
The project aims to study the plasticisation of cellulose derivatives by water and active pharmaceutical ingredients. The project will use and develop scattering techniques and different mechanical, thermal and permeability characterisation techniques such as DMA/DMA+RH, DSC and oxygen permeability at different RH. The purpose is to better understand how cellulose derivatives interact with water as a plasticiser and how that affects the drug release rate.